DHEA Vaginal Suppository

Dehydroepiandrosterone (DHEA) is a synthetic steroid that is chemically identical to the naturally-occurring pro-hormone 5-dehydroepiandrosterone (5-DHEA), a pro-hormone secreted by the adrenal cortex, gonads and brain tissue. The intravaginal DHEA insert is indicated for the treatment of moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. The product provides a non-estrogen, vaginal therapy option to address isolated genitourinary symptoms in these women. DHEA was shown to significantly (p less than 0.05) reduce the severity of pain experienced during sexual intercourse when compared to placebo in two 12-week placebo-controlled clinical trials of 406 healthy postmenopausal women 40 to 80 years of age.